Home Itens selecionados Provedores de dados OAI Créditos Sobre Ajuda

			Busca avançada
	Provedor de dados J. Venom. Anim. Toxins incl. Trop. Dis. (2) Autor Groppo,FC (2) Oshima-Franco,Y (2) Albuquerque,LBL (1) Camargo,TM (1) Cardoso,CRP (1) Cogo,JC (1) Dal Belo,CA (1) Della Torre,A (1) Farrapo,NM (1) Lopes,PS (1) Nazato,VS (1) Rodas,ACD (1) Santos,MG (1) Silva,MG (1) Tavares,RVS (1) Varanda,EA (1) Mais... Palavra-chave Ames test (1) Antibothropic extract (1) Bothrops jararacussu (1) Casearia gossypiosperma Briquet (1) Micronucleus test (1) Mutagenicity (1) Plant extract (1) Plathymenia reticulata (1) Snake venoms (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2011 (1) 2010 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Bothrops jararacussu venom-induced neuromuscular blockade inhibited by Casearia gossypiosperma Briquet hydroalcoholic extract J. Venom. Anim. Toxins incl. Trop. Dis. Camargo,TM; Nazato,VS; Silva,MG; Cogo,JC; Groppo,FC; Oshima-Franco,Y. The hydroalcoholic extract of Casearia gossypiosperma Briquet (Flacourtiaceae) was standardized for the first time through quality control procedures including pharmacognostic methods, fingerprint chromatograms, defined amounts of marker substances and physicochemical characteristics. The pharmacological activity of C. gossypiosperma (Cg) hydroalcoholic extract was assayed by a traditional in vitro test, which involved irreversible neuromuscular blockade induced by Bothrops jararacussu (Bjssu) venom (60 µg/mL) in mouse phrenic nerve-diaphragm preparations. Bjssu venom blocked muscle activity for 26 (± 2.0) minutes (n = 6). Cg extract (0.1 mg/mL) induced changes on the baseline muscle activity without impairing the muscle function and inhibited 87.6% (±... Tipo: Info:eu-repo/semantics/article Palavras-chave: Antibothropic extract; Bothrops jararacussu; Casearia gossypiosperma Briquet; Snake venoms. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000300009 Mutagenicity induced by the hydroalcoholic extract of the medicinal plant Plathymenia reticulata Benth J. Venom. Anim. Toxins incl. Trop. Dis. Della Torre,A; Albuquerque,LBL; Farrapo,NM; Oshima-Franco,Y; Santos,MG; Tavares,RVS; Rodas,ACD; Dal Belo,CA; Cardoso,CRP; Varanda,EA; Groppo,FC; Lopes,PS. Plathymenia reticulata Benth has an anti-inflammatory effect and is capable of neutralizing the neuromuscular blockade induced by Bothrops jararacussu or Crotalus durissus terrificus venoms, probably by precipitating venom proteins (an effect caused by plant tannins). The present study aimed to evaluate the mutagenic activity of P. reticulata by using the Salmonella mutagenicity assay (Ames test) and the micronucleus test in CHO-K1 cells. P. reticulata extract concentrations of 2.84, 5.68, 11.37, and 19.90 mg/plate were assayed by the Ames test using TA97a, TA98, TA100 and TA102 bacterial strains, with (+S9) and without (-S9) metabolic activation. Concentrations of 5, 1.6 and 0.5 μg/mL of P. reticulata extract were used for the micronucleus test. P.... Tipo: Info:eu-repo/semantics/article Palavras-chave: Ames test; Micronucleus test; Mutagenicity; Plant extract; Plathymenia reticulata. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000200010 Registros recuperados: 2 Primeira ... 1 ... Última

Empresa Brasileira de Pesquisa Agropecuária - Embrapa Todos os direitos reservados, conforme Lei n° 9.610 Política de Privacidade Área restrita		Embrapa Parque Estação Biológica - PqEB s/n° Brasília, DF - Brasil - CEP 70770-901 Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco